Efektivitas Intervensi Depresi dan Jumlah CD4 pada Orang yang Hidup dengan HIV
DOI:
https://doi.org/10.32584/jikj.v3i1.473Keywords:
depresi, intervensi, jumlah CD4 pasien HIVAbstract
Acquired Immunodeficiency Syndrome timbul akibat rusaknya sistem kekebalan tubuh manusia yang disebabkan oleh infeksi Human Immunodefiency Virus (HIV). Penderita penyakit HIV/AIDS semakin meningkat secara signifikan setiap tahunnya. Masalah yang dialami ODHA sangat kompleks salah satunya yaitu depresi. Depresi pada pasien HIV/AIDS disebabkan oleh banyak faktor, salah satunya yaitu karena jumlah CD4 yang menurun. Tujuan penelitian ini menggunakan pendekatan systematic review bertujuan untuk memperoleh pemahaman yang lebih tentang intervensi terhadap depresi dan jumlah CD4 pasien HIV. Metode systematic review dilakukan dengan mencari literatur-literatur yang terkait dengan tema yang diambil. Pencarian literatur diambil dari scient direct, EBSCO, proquest dan google scholar. Kata kunci yang dimasukan dalam pencarian artikel ini antara lain “interventionâ€, “depressionâ€, “CD4 count patient HIVâ€. Pencarian literatur dibatasi dari tahun 2014-2020, artikel diseleksi dan didapatkan 18 artikel yang sesuai dengan metode RCT, RCP, quasi experiment dan cross sectional. Hasil artikel yang didapat berasal dari beberapa negara, dari 18 penelitian mayoritas studi dilakukan di negara Indonesia dan dibeberapa negara lainnya, sedangkan intervensi terbanyak yaitu dengan melakukan berbagai macam jenis exercise (yoga, aerobik) dan mindfulness untuk penurunan depresi, sebagiannya dapat meningkatan jumlah CD4 pasien HIV. Kesimpulan tinjauan ini membantu menginformasikan beberapa intervensi yang dapat dilakukan pada ODHA, dapat menghemat biaya dan sederhana untuk dilakukan untuk menurunkan depresi dan meningkatkan jumlah CD4 pada ODHA. Kata kunci: depresi, intervensi, jumlah CD4 pasien HIV EFFECTIVENESS OF DEPRESSION INTERVENTIONS AND CD4 COUNT FOR PEOPLE LIVING WITH HIV ABSTRACTAcquired Immunodeficiency Syndrome (AIDS) arises due to damage to the human immune system caused by infection with the Human Immunodefiency Virus (HIV). HIV / AIDS sufferers are increasing significantly every year. Problems experienced by people living with HIV are very complex one of which is depression. Depression in HIV / AIDS patients is caused by many factors, one of which is due to a decreased CD4 cell count. Purpose this study uses a systematic review approach aimed at gaining a better understanding of interventions for depression and CD4 counts of HIV patients. Method Systematic review is done by looking for literature related to the theme taken. Literature search was taken from scient direct, EBSCO, proquest and google scholar. Keywords included in the search for this article include "intervention", "depression", "CD4 count patient HIV". Literature search was limited from 2014-2020, articles were selected and 18 articles were found in accordance with the RCT, RCP, quasi experiment and cross sectional methods. Results articles obtained from several countries, from 18 studies the majority of studies conducted in Indonesia and in several other countries, while the most interventions are by doing various types of exercise (yoga, aerobics) and mindfulness to reduce depression, some of which can increase the CD4 count of HIV patients / AIDS. Conclusion this review helps inform some of the interventions that can be carried out in people living with HIV, can save costs and is simple to do to reduce depression and increase CD4 counts in people living with HIV. Keywords: depression, intervention, CD4 cell count of HIV patientsReferences
Anderson, R., Freedland, K., RE, C., & Lustman, P. J. (2001). The Prevalence of Comorbid Depression. Diabetes Care, 24(6), 1069–1078.
Aweto, H. A., Aiyegbusi, A. I., Ugonabo, A. J., & Adeyemo, T. A. (2016). Effects of aerobic exercise on the pulmonary functions, respiratory symptoms and psychological status of people living with HIV. Journal of Research in Health Sciences, 16(1), 17–21.
Benton, T. D., Kee Ng, W. Y., Leung, D., Canetti, A., & Karnik, N. (2019). Depression among Youth Living with HIV/AIDS. Child and Adolescent Psychiatric Clinics of North America, 28(3), 447–459. https://doi.org/10.1016/j.chc.2019.02.014
Dianatinasab, M., Fararouei, M., Padehban, V., Dianatinasab, A., Alimohamadi, Y., Beheshti, S., … AminiLari, M. (2018). The effect of a 12-week combinational exercise program on CD4 count and mental health among HIV infected women: A randomized control trial. Journal of Exercise Science and Fitness, 16(1), 21–25. https://doi.org/10.1016/j.jesf.2018.02.001
Gonzalez-Garcia, M., Ferrer, M. J., Borras, X., Muñoz-Moreno, J. A., Miranda, C., Puig, J., … Fumaz, C. R. (2014). Effectiveness of mindfulness-based cognitive therapy on the quality of life, emotional status, and CD4 cell count of patients aging with HIV infection. AIDS and Behavior, 18(4), 676–685. https://doi.org/10.1007/s10461-013-0612-z
Grace, J. M., Semple, S. J., & Combrink, S. (2015). Exercise therapy for human immunodeficiency virus/AIDS patients: Guidelines for clinical exercise therapists. Journal of Exercise Science and Fitness, 13(1), 49–56. https://doi.org/10.1016/j.jesf.2014.10.003
Gregory, R., Gilles, C., Aude, A., Laurie, L., Leïla, B., Jean-Cyr, Y., & Jean-Christophe, M. (2017). Effects of massage therapy on anxiety, depression, hyperventilation and quality of life in HIV infected patients: A randomized controlled trial. Complementary Therapies in Medicine, 32(December 2016), 109–114. https://doi.org/10.1016/j.ctim.2017.05.002
Haglund, M., Ang, A., Mooney, L., Gonzales, R., Chudzynski, J., Cooper, C. B., … Rawson, R. A. (2015). Predictors of depression outcomes among abstinent methamphetamine-dependent individuals exposed to an exercise intervention. American Journal on Addictions, 24(3), 246–251. https://doi.org/10.1111/ajad.12175
Heissel, A., Zech, P., Rapp, M. A., Schuch, F. B., Lawrence, J. B., Kangas, M., & Heinzel, S. (2019). Effects of exercise on depression and anxiety in persons living with HIV: A meta-analysis. Journal of Psychosomatic Research, 126(August), 109823. https://doi.org/10.1016/j.jpsychores.2019.109823
Jaggers, J. R., Dudgeon, W., Blair, S. N., Sui, X., Burgess, S., Wilcox, S., & Hand, G. A. (2013). A home-based exercise intervention to increase physical activity among people living with HIV: Study design of a randomized clinical trial. BMC Public Health, 13(1). https://doi.org/10.1186/1471-2458-13-502
Jensen, W., Oechsle, K., Baumann, H. J., Mehnert, A., Klose, H., Bloch, W., … Baumann, F. T. (2014). Effects of exercise training programs on physical performance and quality of life in patients with metastatic lung cancer undergoing palliative chemotherapy-A study protocol. Contemporary Clinical Trials, 37(1), 120–128. https://doi.org/10.1016/j.cct.2013.11.013
Kemenkes. (2017). Laporan Perkembangan HIV-AIDS. 1–565.
Kusuma, H. (2011). Hubungan Antara Depresi dan Dukungan Keluarga Dengan Kualitas Hidup Pasien HIV/AIDS yang Menjalani Perawatan di RSUP Cipto Mangunkusumo Jakarta. Universitas Indonesia, 20,21,76-79,111-114,135-139. Retrieved from www.lib.ac.id
Lang, C. (1993). Using Relaxation and Exercise as Part of the Care of People Living with HIV/AIDS. Physiotherapy (United Kingdom), 79(6), 379–384. https://doi.org/10.1016/S0031-9406(10)60756-0
LaVoy, E. C., Bosch, J. A., Lowder, T. W., & Simpson, R. J. (2013). Acute aerobic exercise in humans increases cytokine expression in CD27- but not CD27+ CD8+ T-cells. Brain, Behavior, and Immunity, 27(1), 54–62. https://doi.org/10.1016/j.bbi.2012.09.006
Li, L., Lee, S. J., Thammawijaya, P., Jiraphongsa, C., & Rotheram-Borus, M. J. (2009). Stigma, social support, and depression among people living with HIV in Thailand. AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV, 21(8), 1007–1013. https://doi.org/10.1080/09540120802614358
Lox, C. L., McAuley, E., & Tucker, R. S. (1996). Aerobic and resistance exercise training effects on body composition, muscular strength, and cardiovascular fitness in an HIV-1 population. International Journal of Behavioral Medicine, 3(1), 55–69. https://doi.org/10.1207/s15327558ijbm0301_5
Lyon, M. E., Squires, L., D’Angelo, L. J., Benator, D., Scott, R. K., Greenberg, I. H., … Wang, J. (2019). FAmily-CEntered (FACE) Advance Care Planning Among African-American and Non-African-American Adults Living With HIV in Washington, DC: A Randomized Controlled Trial to Increase Documentation and Health Equity. Journal of Pain and Symptom Management, 57(3), 607–616. https://doi.org/10.1016/j.jpainsymman.2018.11.014
McDermott, A., Zaporojan, L., McNamara, P., Doherty, C. P., Redmond, J., Forde, C., … Bergin, C. (2017). The effects of a 16-week aerobic exercise programme on cognitive function in people living with HIV. AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV, 29(6), 667–674. https://doi.org/10.1080/09540121.2016.1263723
Mkandla, K., Myezwa, H., & Musenge, E. (2016). The effects of progressive-resisted exercises on muscle strength and health-related quality of life in persons with HIV-related poly-neuropathy in Zimbabwe. AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV, 28(5), 639–643. https://doi.org/10.1080/09540121.2015.1125418
Muñoz-Moreno, J. A. (2012). HIV & Psychiatry.
Naoroibam, R., Metri, K., Bhargav, H., Nagaratna, R., & Nagendra, H. (2016). Effect of Integrated Yoga (IY) on psychological states and CD4 counts of HIV-1 infected Patients: A Randomized controlled pilot study. International Journal of Yoga, 9(1), 57. https://doi.org/10.4103/0973-6131.171723
Nosrat, S., Whitworth, J. W., Dunsiger, S. I., SantaBarbara, N. J., & Ciccolo, J. T. (2017). Acute effects of resistance exercise in a depressed HIV sample: The exercise for people who are immunocompromised (EPIC) study. Mental Health and Physical Activity, 12, 2–9. https://doi.org/10.1016/j.mhpa.2016.12.002
Nwaka, I. I., Onwunzo, C. N., Ezeakunne, U., Ezeukwu, A. O., Ezugwu, U. A., Chigozie, U. I., & Anieto, E. M. (2019). Effect of Aerobic Exercises and Resistance Exercises on Inflammatory Biomarkers and Fatigue in People Living with HIV Infection Undergoing Highly Active Antiretroviral Therapy; A Systematic Review. Indian Journal of Physiotherapy and Occupational Therapy - An International Journal, 13(4), 174. https://doi.org/10.5958/0973-5674.2019.00156.4
Nyamayaro, P., Bere, T., Magidson, J. F., Simms, V., O’Cleirigh, C., Chibanda, D., & Abas, M. (2019). A Task-Shifting Problem-Solving Therapy Intervention for Depression and Barriers to Antiretroviral Therapy Adherence for People Living With HIV in Zimbabwe: Case Series. Cognitive and Behavioral Practice, #pagerange#. https://doi.org/10.1016/j.jad.2014.02.013
O’Brien, K. K., Tynan, A. M., Nixon, S. A., & Glazier, R. H. (2016). Effectiveness of aerobic exercise for adults living with HIV: Systematic review and meta-analysis using the Cochrane Collaboration protocol. In BMC Infectious Diseases (Vol. 16). https://doi.org/10.1186/s12879-016-1478-2
Patil, R., Shimpi, A., Rairikar, S., Shyam, A., & Sancheti, P. (2017). Effects of fitness training on physical fitness parameters and quality of life in human immunodeficiency virus-positive Indian females. Indian Journal of Sexually Transmitted Diseases, 38(1), 47–53. https://doi.org/10.4103/0253-7184.196886
Petersen, I., Hanass Hancock, J., Bhana, A., & Govender, K. (2014). A group-based counselling intervention for depression comorbid with HIV/AIDS using a task shifting approach in South Africa: A randomized controlled pilot study. Journal of Affective Disorders, 158, 78–84. https://doi.org/10.1016/j.jad.2014.02.013
Robinson, F. P., Mathews, H. L., & Witek-Janusek, L. (2003). Mindfulness-Based Stress Reduction in Individuals Infected with the Human Immunodeficiency Virus : The Journal of Alternative and Complementary Medicine, 9(5), 683–694.
Ruiz S and Pedrol E, R. R. (2012). Physical Activity Associated with HIV. Journal of AIDS & Clinical Research, 03(03), 1–4. https://doi.org/10.4172/2155-6113.s9-001
Safren, S. A., Bedoya, C. A., O’Cleirigh, C., Biello, K. B., Pinkston, M. M., Stein, M. D., … Mayer, K. H. (2016). Cognitive behavioural therapy for adherence and depression in patients with HIV: a three-arm randomised controlled trial. The Lancet HIV, 3(11), e529–e538. https://doi.org/10.1016/S2352-3018(16)30053-4
Sri Suyanti, T., Anna Keliat, B., & Catharina Daulima, N. H. (2018). Effect of logo-therapy, acceptance, commitment therapy, family psychoeducation on self-stigma, and depression on housewives living with HIV/AIDS. Enfermeria Clinica, 28, 98–101. https://doi.org/10.1016/S1130-8621(18)30046-9
Susanti, E., & Beny, R. (2014). Effect of Locus of Control and Peer Support the Risk of Depression on People Living with HIV / AIDS in KDS Friendship Plus Kediri City. 2014(September), 228–235.
Unaids. (2019). 2018 Global HIV Statistics. 2(1), 1–6.
Valeria, J., Surilena, S., Budiman, Y., Djauzi, S., & Indah, H. (2016). Family support is not a risk factor of negative self-esteem in HIV/AIDS women. Universa Medicina, 34(1), 61. https://doi.org/10.18051/univmed.2015.v34.61-67
Yang, Y., Liu, Y. H., Zhang, H. F., & Liu, J. Y. (2015). Effectiveness of mindfulness-based stress reduction and mindfulness-based cognitive therapies on people living with HIV: A systematic review and meta-analysis. International Journal of Nursing Sciences, 2(3), 283–294. https://doi.org/10.1016/j.ijnss.2015.07.003
Zhao, L., Wu, H., Zhou, X., Wang, Q., Zhu, W., & Chen, J. (2012). Effects of progressive muscular relaxation training on anxiety, depression and quality of life of endometriosis patients under gonadotrophin-releasing hormone agonist therapy. European Journal of Obstetrics and Gynecology and Reproductive Biology, 162(2), 211–215. https://doi.org/10.1016/j.ejogrb.2012.02.029
Downloads
Published
How to Cite
Issue
Section
License
Authors who publish with this journal agree to the following terms:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
This work is licensed under a Creative Commons Attribution 4.0 International License.